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Homocysteine, Alzheimer's disease, and cognitive function.

作者信息

Miller J W

机构信息

Department of Medical Pathology, School of Medicine, University of California at Davis, 95817, USA.

出版信息

Nutrition. 2000 Jul-Aug;16(7-8):675-7. doi: 10.1016/s0899-9007(00)00307-5.

DOI:10.1016/s0899-9007(00)00307-5
PMID:10906594
Abstract
摘要

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Homocysteine, Alzheimer's disease, and cognitive function.同型半胱氨酸、阿尔茨海默病与认知功能。
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Elevated plasma homocysteine level is not primarily related to Alzheimer's disease.血浆同型半胱氨酸水平升高与阿尔茨海默病并无直接关系。
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钙从神经元中输出和多激酶信号级联反应有助于高同型半胱氨酸血症中海奥巴因的神经保护作用。
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Lowering homocysteine levels with folic acid and B-vitamins do not reduce early atherosclerosis, but could interfere with cognitive decline and Alzheimer's disease.用叶酸和 B 族维生素降低同型半胱氨酸水平并不能减少早期动脉粥样硬化，但可能会干扰认知能力下降和阿尔茨海默病。
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Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats.孕期维生素B缺乏会导致同型半胱氨酸相关的脑凋亡，并改变大鼠的神经行为发育。
Am J Pathol. 2007 Feb;170(2):667-79. doi: 10.2353/ajpath.2007.060339.
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Homocysteine and cognitive function in institutionalised elderly A cross-sectional analysis.机构养老老年人的同型半胱氨酸与认知功能：一项横断面分析
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