胸腺来源淋巴细胞在体液免疫和细胞介导免疫中的玫瑰花结形成能力。II. 辅助细胞活性。
Rosette-forming ability of thymus-derived lymphocytes in humoral and cell-mediated immunity. II. Helper cell activity.
作者信息
Elliott B E, Haskill J S
出版信息
J Exp Med. 1975 Mar 1;141(3):600-7. doi: 10.1084/jem.141.3.600.
Abstract
The technique of velocity sedimentation at unit gravity was used to determine the size and rosette-forming ability of helper cells in nonimmune and immune C57BL/6 mice. Helper T cells were assayed by the ability to cooperate with bone barrow (B) cells in the antibody response to sheep erythrocytes (SRBC) in vivo. 19S helper cells in nonimmune animals were nonrosette-forming small lymphocytes; after immunization with SRBC in complete Freund's adjuvant, 19S helper cells were nonrosette-forming medium lymphocytes. 7S helper cells in immune animals were small lymphocytes which did not form rosettes. No SRBC binding by helper cells was observed under the conditions of rosette formation used.
摘要
采用单位重力下的速度沉降技术，来测定非免疫和免疫的C57BL/6小鼠中辅助细胞的大小及形成玫瑰花结的能力。通过在体内对绵羊红细胞（SRBC）的抗体反应中，辅助性T细胞与骨髓（B）细胞协同作用的能力来进行测定。非免疫动物中的19S辅助细胞是不形成玫瑰花结的小淋巴细胞；在用完全弗氏佐剂免疫SRBC后，19S辅助细胞是不形成玫瑰花结的中等大小淋巴细胞。免疫动物中的7S辅助细胞是不形成玫瑰花结的小淋巴细胞。在所采用的玫瑰花结形成条件下，未观察到辅助细胞与SRBC结合。
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Rosette-forming ability of thymus-derived lymphocytes in humoral and cell-mediated immunity. II. Helper cell activity.胸腺来源淋巴细胞在体液免疫和细胞介导免疫中的玫瑰花结形成能力。II. 辅助细胞活性。
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Immunology. 1968 Apr;14(4):599-600.
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Cell cooperation in antibody induction. The susceptibility of helper cells to specific lethal radioactive antigen.抗体诱导中的细胞合作。辅助细胞对特异性致死性放射性抗原的敏感性。
Eur J Immunol. 1971 Jun;1(3):151-7. doi: 10.1002/eji.1830010302.
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Antigen binding cells in tolerance and immunity.耐受性和免疫中的抗原结合细胞。
Transplant Rev. 1970;5:105-29. doi: 10.1111/j.1600-065x.1970.tb00358.x.
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Specific fractionation of immunocompetent cells.免疫活性细胞的特异性分级分离
Transplant Rev. 1970;5:76-104. doi: 10.1111/j.1600-065x.1970.tb00357.x.
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Immune responses in vitro. 3. Development of primary gamma-M, gamma-G, and gamma-A plaque-forming cell responses in mouse spleen cell cultures stimulated with heterologous erythrocytes.体外免疫反应。3. 用异种红细胞刺激小鼠脾细胞培养物中主要γ-M、γ-G和γ-A斑块形成细胞反应的发展。
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