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1
Rosette-forming ability of thymus-derived lymphocytes in humoral and cell-mediated immunity. II. Helper cell activity.胸腺来源淋巴细胞在体液免疫和细胞介导免疫中的玫瑰花结形成能力。II. 辅助细胞活性。
J Exp Med. 1975 Mar 1;141(3):600-7. doi: 10.1084/jem.141.3.600.
2
Thymus-derived rosettes are not "helper" cells.胸腺来源的玫瑰花结不是“辅助”细胞。
J Exp Med. 1973 Nov 1;138(5):1133-43. doi: 10.1084/jem.138.5.1133.
3
The immune response of mice treated with anti-mu antibodies: the effect on antibody-forming cells, their precursors and helper cells assayed in vitro.用抗μ抗体处理的小鼠的免疫反应：对体外测定的抗体形成细胞、其前体和辅助细胞的影响。
J Immunol. 1975 Jun;114(6):1808-12.
4
Rosette-forming ability of thymus-derived lymphocytes in cell-mediated immunity. I. Delayed hypersensitivity and in vitro cytotoxicity.细胞介导免疫中胸腺衍生淋巴细胞的玫瑰花结形成能力。I. 迟发型超敏反应和体外细胞毒性。
J Exp Med. 1975 Mar 1;141(3):584-99. doi: 10.1084/jem.141.3.584.
5
Rosette formation with sheep erythrocytes--a possible T-cell marker in the pig.与绵羊红细胞形成玫瑰花结——猪体内一种可能的T细胞标志物。
Int Arch Allergy Appl Immunol. 1975;48(2):261-75. doi: 10.1159/000231312.
6
Antigenic characterization of murine rosette and plaque-forming cells.小鼠玫瑰花结形成细胞和空斑形成细胞的抗原特性
Immunology. 1973 Jun;24(6):939-54.
7
The functions of immune T and B rosette-forming cells.免疫T和B玫瑰花结形成细胞的功能。
Immunology. 1973 Aug;25(2):158-96.
8
Antibody formation in mouse bone marrow. IV. The influence of splenectomy on the bone marrow plaque-forming cell response to sheep red blood cells.小鼠骨髓中的抗体形成。IV. 脾切除对骨髓中针对绵羊红细胞的噬斑形成细胞反应的影响。
Cell Immunol. 1975 Oct;19(2):167-82. doi: 10.1016/0008-8749(75)90201-4.
9
Immune response against hamster erythrocytes in the low-responder mouse strains. X. Proliferation of antibody-forming cells after antigenic stimulation of mice with different activities of thymus-derived lymphocytes.低反应性小鼠品系对仓鼠红细胞的免疫反应。十、用不同活性的胸腺衍生淋巴细胞对抗原刺激后的小鼠抗体形成细胞的增殖。
Jpn J Microbiol. 1974 Jul;18(4):265-70. doi: 10.1111/j.1348-0421.1974.tb00809.x.
10
Effect of recent antigen priming on adoptive immune responses. I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes.近期抗原致敏对过继免疫反应的影响。I. 用异种红细胞致敏的小鼠淋巴器官细胞的特异性无反应性。
J Exp Med. 1973 Jul 1;138(1):143-62. doi: 10.1084/jem.138.1.143.

引用本文的文献

1
Depletion by monolayer binding of specific precursors of antibody-forming cells directed against cellular antigens.通过单层结合针对细胞抗原的抗体形成细胞的特定前体来消耗。
Immunology. 1986 Mar;57(3):411-7.
2
Helper T-cell kinetics and investigation of antigen receptor expression on early and memory T-helper cells.辅助性T细胞动力学及早期和记忆性辅助性T细胞上抗原受体表达的研究
Immunology. 1976 Aug;31(2):249-55.
3
Cell-mediated and humoral immune responses in mice. IV. Difference of the functional cell population between helper activity and delayed-type hypersensitivity.小鼠的细胞介导免疫和体液免疫反应。IV. 辅助活性和迟发型超敏反应之间功能细胞群的差异。
Immunology. 1977 Mar;32(3):237-45.
4
Changes in the population and functional properties of antigen-specific rosette-forming B cells in antigen-primed mice by administration of polyclonal B-cell activator.通过给予多克隆B细胞激活剂对抗原致敏小鼠中抗原特异性玫瑰花结形成B细胞的群体和功能特性的影响。
Immunology. 1978 Jul;35(1):85-94.
5
Antigen-binding T cells as helper cells. Separation of helper cells by immune rosette formation.作为辅助细胞的抗原结合性T细胞。通过免疫玫瑰花结形成分离辅助细胞。
J Exp Med. 1975 Oct 1;142(4):1035-9. doi: 10.1084/jem.142.4.1035.

本文引用的文献

1
Further improvements in the plaque technique for detecting single antibody-forming cells.用于检测单个抗体形成细胞的蚀斑技术的进一步改进。
Immunology. 1968 Apr;14(4):599-600.
2
Cell cooperation in antibody induction. The susceptibility of helper cells to specific lethal radioactive antigen.抗体诱导中的细胞合作。辅助细胞对特异性致死性放射性抗原的敏感性。
Eur J Immunol. 1971 Jun;1(3):151-7. doi: 10.1002/eji.1830010302.
3
Antigen binding cells in tolerance and immunity.耐受性和免疫中的抗原结合细胞。
Transplant Rev. 1970;5:105-29. doi: 10.1111/j.1600-065x.1970.tb00358.x.
4
Specific fractionation of immunocompetent cells.免疫活性细胞的特异性分级分离
Transplant Rev. 1970;5:76-104. doi: 10.1111/j.1600-065x.1970.tb00357.x.
5
Immune responses in vitro. 3. Development of primary gamma-M, gamma-G, and gamma-A plaque-forming cell responses in mouse spleen cell cultures stimulated with heterologous erythrocytes.体外免疫反应。3. 用异种红细胞刺激小鼠脾细胞培养物中主要γ-M、γ-G和γ-A斑块形成细胞反应的发展。
J Exp Med. 1971 Aug 1;134(2):395-416. doi: 10.1084/jem.134.2.395.
6
Lymphocyte proliferation in vitro induced by hapten autologous protein conjugates. I. A study on the class of lymphocytes responding in vitro and on the nature and specificity of their receptors.半抗原自体蛋白缀合物诱导的体外淋巴细胞增殖。I. 体外应答淋巴细胞类别及其受体性质和特异性的研究
J Exp Med. 1974 Mar 1;139(3):732-53. doi: 10.1084/jem.139.3.732.
7
Dose dependence of antigen binding to B and T lymphocytes.抗原与B淋巴细胞和T淋巴细胞结合的剂量依赖性。
Nature. 1974 Jan 11;247(5436):104-6. doi: 10.1038/247104a0.
8
The functions of immune T and B rosette-forming cells.免疫T和B玫瑰花结形成细胞的功能。
Immunology. 1973 Aug;25(2):158-96.
9
Cooperation and cell-mediated cytotoxicity as functions of two subsets of T cells.作为T细胞两个亚群功能的协同作用和细胞介导的细胞毒性。
J Immunol. 1974 Nov;113(5):1553-61.
10
Tolerance, enhancement and the regulation of interactions between T cells, B cells and macrophages.耐受性、增强作用以及T细胞、B细胞与巨噬细胞之间相互作用的调节
Transplant Rev. 1972;13:3-34. doi: 10.1111/j.1600-065x.1972.tb00058.x.

胸腺来源淋巴细胞在体液免疫和细胞介导免疫中的玫瑰花结形成能力。II. 辅助细胞活性。

Rosette-forming ability of thymus-derived lymphocytes in humoral and cell-mediated immunity. II. Helper cell activity.

作者信息

Elliott B E, Haskill J S

出版信息

J Exp Med. 1975 Mar 1;141(3):600-7. doi: 10.1084/jem.141.3.600.

DOI:10.1084/jem.141.3.600
PMID:1090701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2189711/
Abstract

The technique of velocity sedimentation at unit gravity was used to determine the size and rosette-forming ability of helper cells in nonimmune and immune C57BL/6 mice. Helper T cells were assayed by the ability to cooperate with bone barrow (B) cells in the antibody response to sheep erythrocytes (SRBC) in vivo. 19S helper cells in nonimmune animals were nonrosette-forming small lymphocytes; after immunization with SRBC in complete Freund's adjuvant, 19S helper cells were nonrosette-forming medium lymphocytes. 7S helper cells in immune animals were small lymphocytes which did not form rosettes. No SRBC binding by helper cells was observed under the conditions of rosette formation used.

摘要

采用单位重力下的速度沉降技术，来测定非免疫和免疫的C57BL/6小鼠中辅助细胞的大小及形成玫瑰花结的能力。通过在体内对绵羊红细胞（SRBC）的抗体反应中，辅助性T细胞与骨髓（B）细胞协同作用的能力来进行测定。非免疫动物中的19S辅助细胞是不形成玫瑰花结的小淋巴细胞；在用完全弗氏佐剂免疫SRBC后，19S辅助细胞是不形成玫瑰花结的中等大小淋巴细胞。免疫动物中的7S辅助细胞是不形成玫瑰花结的小淋巴细胞。在所采用的玫瑰花结形成条件下，未观察到辅助细胞与SRBC结合。