Arnavielhe S, De Meeüs T, Blancard A, Mallié M, Renaud F, Bastide J M
Centre d'Etude sur le Polymorphisme des Micro-Organismes, Equipe: Evolution des Systémes Symbiotiques', Montpellier, France.
Mycoses. 2000;43(3-4):109-17. doi: 10.1046/j.1439-0507.2000.00552.x.
A mycological survey was conducted on non-neutropenic patients in three distinct intensive care units in two hospitals in Marseille (France) from November 1993 to November 1995. Candida albicans positive cultures from 62 patients were included in this study. Every first isolate of each patient was typed by multilocus enzyme electrophoresis (MLEE). The enzyme profiles obtained from 15 polymorphic loci were then compared. This analysis demonstrated a strong population differentiation of C. albicans infective strains within and between the different care units and confirmed the probable preponderant clonal mode of reproduction of this yeast.
1993年11月至1995年11月，在法国马赛的两家医院的三个不同重症监护病房对非中性粒细胞减少患者进行了真菌学调查。本研究纳入了62例白色念珠菌阳性培养患者。对每位患者的首个分离株进行多位点酶电泳（MLEE）分型。然后比较从15个多态性位点获得的酶谱。该分析表明，不同护理单元内部和之间的白色念珠菌感染菌株存在强烈的群体分化，并证实了这种酵母可能主要的克隆繁殖模式。
