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通过多态性微卫星位点分析对健康个体口腔白色念珠菌菌株进行基因分型。

Genotyping of Candida albicans oral strains from healthy individuals by polymorphic microsatellite locus analysis.

作者信息

Dalle Frédéric, Dumont Laure, Franco Norélie, Mesmacque David, Caillot Denis, Bonnin Pierre, Moiroux Caroline, Vagner Odile, Cuisenier Bernadette, Lizard Sarab, Bonnin Alain

机构信息

Laboratoire de Parasitologie et Mycologie, CHU et Faculté de Médecine, Dijon, France.

出版信息

J Clin Microbiol. 2003 May;41(5):2203-5. doi: 10.1128/JCM.41.5.2203-2205.2003.

DOI:10.1128/JCM.41.5.2203-2205.2003
PMID:12734280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC154696/
Abstract

Analysis of a polymorphic microsatellite locus was applied to 85 Candida albicans strains from healthy individuals. Comparison with strains from nonhealthy individuals previously analyzed in our laboratory showed an overall similarity, suggesting that all commensal strains have the ability to develop as pathogens.

摘要

对来自健康个体的85株白色念珠菌菌株进行了多态性微卫星位点分析。与我们实验室之前分析的来自非健康个体的菌株进行比较，结果显示总体相似，这表明所有共生菌株都有发展成为病原体的能力。

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本文引用的文献

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Ca3 fingerprinting of Candida albicans isolates from human immunodeficiency virus-positive and healthy individuals reveals a new clade in South Africa.对来自人类免疫缺陷病毒阳性个体和健康个体的白色念珠菌分离株进行的Ca3指纹图谱分析揭示了南非的一个新分支。
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Analysis of microsatellite markers of Candida albicans used for rapid typing.用于快速分型的白色念珠菌微卫星标记分析。
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Adherence and invasion studies of Candida albicans strains, using in vitro models of esophageal candidiasis.利用食管念珠菌病的体外模型对白色念珠菌菌株进行黏附和侵袭研究。
J Infect Dis. 2001 Nov 1;184(9):1170-5. doi: 10.1086/323807. Epub 2001 Oct 12.
4
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5
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J Clin Microbiol. 2000 Dec;38(12):4554-9. doi: 10.1128/JCM.38.12.4554-4559.2000.
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Evidence for a general-purpose genotype in Candida albicans, highly prevalent in multiple geographical regions, patient types and types of infection.
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Microbiology (Reading). 1999 May;145 ( Pt 5):1137-1143. doi: 10.1099/13500872-145-5-1137.
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