Matowicka-Karna J, Mantur M, Kemona H, Prokopowicz J, Darewicz B
Zakład Laboratoryjnej Diagnostyki Klinicznej Instytutu Diagnostyki Laboratoryjnej, Akademii Medycznej w Białymstoku.
Przegl Lek. 2000;57(1):29-31.
Embolization consists in the occlusion of renal artery and its ramifications, which induces acute renal infarction. Renal artery embolization, causing necrosis, stimulates cellular reactions within and around the neoplasm. The interaction of neoplastic cells with blood platelets is of great importance in the development of neoplastic disease. Neoplastic cells exert a stimulatory effect on blood platelets. During activation, platelets change in shape and secrete certain substances. We conducted this study measuring the phagocytic activity of blood platelets. 45 patients suffering from renal cancer were examined (22 women and 23 men) before and after embolization. Diagnosis was established basing on the patients' history, clinical picture, and ultrasonographic, urographic and angiographic examinations. The study demonstrated that embolization led to an increase in platelet count and decrease of phagocytic index.
栓塞术包括闭塞肾动脉及其分支，从而引发急性肾梗死。肾动脉栓塞导致坏死，刺激肿瘤内部及周围的细胞反应。肿瘤细胞与血小板的相互作用在肿瘤疾病的发展中至关重要。肿瘤细胞对血小板发挥刺激作用。在激活过程中，血小板会改变形状并分泌某些物质。我们开展了这项研究，测量血小板的吞噬活性。对45例肾癌患者（22名女性和23名男性）在栓塞前后进行了检查。根据患者病史、临床表现以及超声、尿路造影和血管造影检查来确诊。研究表明，栓塞导致血小板计数增加，吞噬指数降低。
