Schwartz M, Le Minor L
J Virol. 1975 Apr;15(4):679-85. doi: 10.1128/JVI.15.4.679-685.1975.
In Escherichia coli K-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. Lambda receptor activity was found in extracts from all wild strains of E. coli tested, although most of them fail to support growth of the phage. In some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. In other cases, adsorption does occur, and the nature of the block in phage growth was not investigated. Most Mal+ strains of Shigella have lambda receptor, whereas most Mal- strains do not have it. Synthesis of the lambda receptor in Shigella is thus presumably controlled by the positive regulator gene of the maltose regulon as is the case in E. coli K-12. Phage lambda adsorbs on many Mal+ strains of Shigella and even yields plaques on some of them, although at a low frequency. No lambda receptor activity could be found in extracts of several strains of Salmonella and Levinea.
在大肠杆菌K-12中，噬菌体λ的受体是一种外膜蛋白，它在体外可使噬菌体失活。在所测试的所有大肠杆菌野生菌株的提取物中都发现了λ受体活性，尽管其中大多数菌株不能支持噬菌体生长。在某些情况下，这种失败是由于受体在体内被掩盖，细菌无法吸附噬菌体或与抗受体抗体发生反应。在其他情况下，吸附确实会发生，但未对噬菌体生长受阻的性质进行研究。大多数志贺氏菌的Mal+菌株具有λ受体，而大多数Mal-菌株则没有。因此，志贺氏菌中λ受体的合成大概像在大肠杆菌K-12中一样受麦芽糖操纵子的正调控基因控制。噬菌体λ吸附在许多志贺氏菌的Mal+菌株上，甚至在其中一些菌株上形成噬菌斑，尽管频率较低。在几种沙门氏菌和勒维氏菌菌株的提取物中未发现λ受体活性。
