Meyerowitz B E, Sparks F C, Spears I K
Cancer. 1979 May;43(5):1613-8. doi: 10.1002/1097-0142(197905)43:5<1613::aid-cncr2820430508>3.0.co;2-8.
Fifty women receiving adjuvant chemotherapy after surgery for Stage II breast carcinoma were interviewed in an effort to describe the psychosocial effect of the treatment. Perceptions of emotional distress and behavioral disruption were rated in five areas, yielding a rating of overall level of disruption and distress. Results showed that all women experienced adverse changes while receiving adjuvant treatments. Of the 50 women, 88% described a decrease in activities related to the effects of adjuvant chemotherapy; 54% reported an increased financial burden; and 41% claimed that their family and/or sexual life had been adversely affected. Despite these adverse changes, 74% of these patients "would definitely" recommend the treatment to friends in a similar situation. Results from this preliminary study may provide useful information to potential participants in adjuvant trials and to the physicians who conduct such trials.
为了描述辅助化疗对心理社会的影响，研究人员对50名接受II期乳腺癌手术后辅助化疗的女性进行了访谈。从五个方面对她们的情绪困扰和行为紊乱认知进行评分，得出整体紊乱和困扰程度的评分。结果显示，所有女性在接受辅助治疗期间都经历了不良变化。在这50名女性中，88%表示与辅助化疗副作用相关的活动减少；54%称经济负担加重；41%声称她们的家庭和/或性生活受到了不利影响。尽管有这些不良变化，但74%的患者“肯定会”向处于类似情况的朋友推荐这种治疗方法。这项初步研究的结果可能会为辅助化疗试验的潜在参与者以及开展此类试验的医生提供有用信息。
