Masquelet A C, Fitoussi F, Begue T, Muller G P
Service de chirurgie orthopédique, traumatologique et réparatrice, hôpital Avicenne, université Paris XIII, Bobigny, France.
Ann Chir Plast Esthet. 2000 Jun;45(3):346-53.
In the reported series of 35 cases bone reconstruction of large diaphyseal defects was performed in two stages. The first stage was the insertion into the defect of a cement spacer which was responsible for the formation of a pseudosynovial membrane. The second stage was the reconstruction of the defect by a huge fresh autologous cancellous bone graft. The membrane induced by the spacer prevents the resorption of the graft and favors its vascularity and its corticalisation. In weight bearing diaphyseal segments the normal walking was possible at 8.5 months on average. The length of the reconstructed defects was 4 to 25 cm.
在报道的35例病例系列中,大段骨干缺损的骨重建分两期进行。第一期是在缺损处植入骨水泥间隔物,该间隔物负责形成假滑膜。第二期是用大量新鲜自体松质骨移植重建缺损。间隔物诱导形成的膜可防止移植骨吸收,并有利于其血管化和皮质化。在负重骨干节段,平均8.5个月时即可正常行走。重建缺损的长度为4至25厘米。