Weidanz W P, Rank R G
Proc Soc Exp Biol Med. 1975 Mar;148(3):725-8.
Experimental infection of chickens with P. gallinaceum mardedly suppressed the splenic PFC response to SRBC. Suppression was most pronounced when birds were immunized at the time of peak parasitemia. The PFC response to E. coli LPS was of low magnitiude in both normal and infected chickens; however, it, too, was suppressed in infected birds, but not to the same degree as observed in response to SRBC. Cellular immunity as evidenced by allograft rejection was not influenced by infection.
用鸡疟原虫对鸡进行实验性感染,显著抑制了脾脏对绵羊红细胞的空斑形成细胞反应。当鸡在寄生虫血症高峰期进行免疫时,抑制作用最为明显。正常鸡和感染鸡对大肠杆菌脂多糖的空斑形成细胞反应强度都较低;然而,感染鸡的这种反应也受到了抑制,但程度不如对绵羊红细胞的反应那么明显。以同种异体移植排斥反应为证据的细胞免疫不受感染影响。