约氏疟原虫感染小鼠脾脏细胞的体外抗体应答
Antibody response in vitro of spleen cells from Plasmodium yoelii-infected mice.
作者信息
Brown I N, Watson S R, Sljivić V S
出版信息
Infect Immun. 1977 May;16(2):456-60. doi: 10.1128/iai.16.2.456-460.1977.
Abstract
The primary antibody response to sheep erythrocytes and dinitrophenylated Ficoll of spleen cells from mice infected with Plasmodium yoelii was studied in vitro. The response to sheep erythrocytes was enhanced between 2 and 4 days after infection and depressed at later intervals. Cell fractionation experiments carried out at the time of immunosuppression indicated a defect of macrophage function. At the same time the response to dinitrophenylated Ficoll was normal.
摘要
对感染约氏疟原虫小鼠脾脏细胞针对绵羊红细胞和二硝基苯基化聚蔗糖的初次抗体反应进行了体外研究。感染后2至4天对绵羊红细胞的反应增强，而在之后的时间段则受到抑制。在免疫抑制时进行的细胞分级分离实验表明巨噬细胞功能存在缺陷。与此同时，对二硝基苯基化聚蔗糖的反应正常。
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本文引用的文献
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