Piccolo I, Thiella G, Sterzi R, Colombo N, Defanti C A
Division of Neurology, Hospital Niguarda Ca' Granda, Milan, Italy.
Ital J Neurol Sci. 1998 Aug;19(4):235-9. doi: 10.1007/BF02427611.
Borrelia burgdorferi (Bb) can cause a large number of neurological symptoms. Although extrapyramidal disturbances are rare (representing less than 2% of all neurological complications), diffuse choreic dyskinesias have been described during the course of mild encephalitis. The data published in the literature suggest that there are clinical and neurological analogies between neuroborreliosis and multiple sclerosis (MS). The presence of specific anti-Bb antibodies in cerebrospinal fluid is a discriminating factor that allows a diagnosis of neuroborreliosis to be made. We describe the case of a patient with Lyme disease, characterised by widespread chorea and behavioural disturbances. Emphasis is placed on the atypical onset and evolution, the difficulties encountered in formulating a diagnosis, and the uncertainties concerning the pathophysiology and clinical/neuroradiological correlations of the disease.
伯氏疏螺旋体（Bb）可引发大量神经症状。尽管锥体外系障碍较为罕见（在所有神经并发症中占比不到2%），但在轻度脑炎病程中曾有弥漫性舞蹈样运动障碍的描述。文献中发表的数据表明，神经莱姆病与多发性硬化症（MS）之间存在临床和神经学上的相似之处。脑脊液中特异性抗Bb抗体的存在是一个鉴别因素，有助于做出神经莱姆病的诊断。我们描述了一例莱姆病患者的病例，其特征为广泛的舞蹈症和行为障碍。重点关注非典型的起病和病程、诊断过程中遇到的困难以及该疾病病理生理学和临床/神经放射学相关性方面的不确定性。
