Suppr超能文献

[阿尔科伊健康区多发性硬化症的患病率]

[The prevalence of multiple sclerosis in the Alcoi Health district].

作者信息

Mallada-Frechín J, Matías-Guiu Guía J, Martín R, López-Arlandis J M, Camacho-Cuartero J M, Beltrán I, Moltó J M, Falip R, Abellán-Miralles I

机构信息

Unidad de Neurología, Hospital de Elda, España.

出版信息

Rev Neurol. 2000;30(12):1131-4.

Abstract

INTRODUCTION

The epidemiological studies done in Spain in recent years show higher figures for the prevalence of multiple sclerosis than before. Spain is therefore now in the area with a high risk of contracting the disease.

OBJECTIVE

We have made a new study to confirm the current prevalence of the disorder in the Alcoi Health District.

PATIENTS AND METHODS

Between 1 March 1986 and the prevalence day, 31 December 1997 we recorded the patients with definite or probable multiple sclerosis, as defined on Poser's criteria, after intensive fieldwork and reevaluation of all possible patients by a neurologist from the Neurology Unit. On the prevalence day there were 130,786 inhabitants in the district.

RESULTS

On the prevalence day we found 54 patients with definite multiple sclerosis and no patient with probable multiple sclerosis. The rate of prevalence was 41.28 cases per 100,000 inhabitants (95% CI: 31-53.6). During the study we counted an incidence of 45 cases with an average rate of 2.82 cases per 100,000 inhabitants per year. We also describe the clinical characteristics of the patients.

CONCLUSIONS

The rate of prevalence found is much higher than that described for the district in studies using similar methodology. This increase, together with the discrepancy between the incidence found and the prevalence, makes us consider that possibly the prevalence has increased in recent years.

摘要

引言

近年来在西班牙开展的流行病学研究显示,多发性硬化症的患病率高于以往。因此,西班牙目前处于该病的高风险地区。

目的

我们开展了一项新研究,以确认阿尔科伊健康区该疾病的当前患病率。

患者与方法

在1986年3月1日至患病率统计日(1997年12月31日)期间,我们记录了符合波泽尔标准定义的确诊或可能患有多发性硬化症的患者,这是在经过深入的实地调查并由神经科的一名神经科医生对所有可能的患者进行重新评估之后得出的。在患病率统计日,该地区有130,786名居民。

结果

在患病率统计日,我们发现54例确诊为多发性硬化症的患者,没有可能患有多发性硬化症的患者。患病率为每10万居民中有41.28例(95%可信区间:3l - 53.6)。在研究期间,我们统计到发病率为每年每10万居民中有2.82例,共45例。我们还描述了患者的临床特征。

结论

所发现的患病率远高于使用类似方法对该地区进行研究所描述的患病率。这种上升,以及所发现的发病率与患病率之间的差异,使我们认为近年来患病率可能有所上升。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验