Ares B, Prieto J M, Lema M, Dapena D, Arias M, Noya M
Department of Neurology, Hospital Clínico Universitario, Institute of Neurological Sciences of Galicia P Barrié de la Maza, Santiago de Compostela, Spain.
Mult Scler. 2007 Mar;13(2):262-4. doi: 10.1177/1352458506069540. Epub 2007 Jan 29.
Multiple sclerosis (MS) is the most common central nervous system disease in young adults, and one of the leading causes of disability in this age group.
To establish the prevalence and incidence of MS in Santiago de Compostela (Spain). Material and methods We performed a prospective, case-finding study on > 90,188 inhabitants, from 1 January 1998 to 15 September 2003, selected as day of prevalence. Sources of information were the University Clinical Hospital of Santiago, the hospitals and private clinics of the city, rehabilitators, pediatricians, ophthalmologists, psychiatrists, neurosurgeons, specialists in internal medicine, primary care physicians, association of patients of MS, social services and nongovernmental and religious associations. Informative days were programmed for the susceptible population, and campaigns were carried out in the media. All patients with Poser diagnostic criteria for MS, on the census of Santiago de Compostela as of 15 September 2003, were included in the study.
On the day of prevalence, 71 patients with MS were registered on the census of Santiago de Compostela, therefore, the prevalence was 79 cases per 100,000 inhabitants. The incidence of the disease in the study period was 5.3 cases per 100,000 inhabitants and year.
The prevalence and incidence rates of MS found in Santiago de Compostela are the highest reported, to date, in Spain.
多发性硬化症（MS）是年轻成年人中最常见的中枢神经系统疾病，也是该年龄组致残的主要原因之一。
确定西班牙圣地亚哥-德孔波斯特拉市MS的患病率和发病率。材料与方法 我们于1998年1月1日至2003年9月15日对90188多名居民进行了一项前瞻性病例发现研究，选定该日作为患病率统计日。信息来源包括圣地亚哥大学临床医院、该市的医院和私人诊所、康复治疗师、儿科医生、眼科医生、精神科医生、神经外科医生、内科专家、初级保健医生、MS患者协会、社会服务机构以及非政府和宗教协会。为易感人群安排了信息采集日，并在媒体上开展了宣传活动。所有符合波塞尔（Poser）MS诊断标准且截至2003年9月15日在圣地亚哥-德孔波斯特拉市人口普查中的患者均纳入本研究。
在患病率统计日，圣地亚哥-德孔波斯特拉市人口普查登记了71例MS患者，因此，患病率为每10万居民79例。研究期间该病的发病率为每10万居民每年5.3例。
圣地亚哥-德孔波斯特拉市发现的MS患病率和发病率是迄今为止西班牙报告的最高值。
