Cameron G G, Pomahac A C, Johnston M T
Can Med Assoc J. 1975 Jun 14;112(13 Spec No):87-8.
Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection. They received either of these two agents according to a double-blind randomized procedure that also took the child's weight into account. No significant difference was found in the clinical outcome between the two treatment regimens. Undesirable side effects from TMP-SMX were notably few.
79名患有急性中耳炎的儿童参与了一项研究,该研究旨在比较氨苄青霉素和甲氧苄啶-磺胺甲恶唑在这种感染中的疗效。根据双盲随机程序,同时考虑孩子的体重,他们接受了这两种药物中的一种。两种治疗方案的临床结果没有显著差异。甲氧苄啶-磺胺甲恶唑的不良副作用明显较少。