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氨苄西林与甲氧苄啶-磺胺甲恶唑治疗中耳炎的疗效比较

Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.

作者信息

Cameron G G, Pomahac A C, Johnston M T

出版信息

Can Med Assoc J. 1975 Jun 14;112(13 Spec No):87-8.

Abstract

Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection. They received either of these two agents according to a double-blind randomized procedure that also took the child's weight into account. No significant difference was found in the clinical outcome between the two treatment regimens. Undesirable side effects from TMP-SMX were notably few.

摘要

79名患有急性中耳炎的儿童参与了一项研究,该研究旨在比较氨苄青霉素和甲氧苄啶-磺胺甲恶唑在这种感染中的疗效。根据双盲随机程序,同时考虑孩子的体重,他们接受了这两种药物中的一种。两种治疗方案的临床结果没有显著差异。甲氧苄啶-磺胺甲恶唑的不良副作用明显较少。

本文引用的文献

2
Trimethoprim-sulfamethoxazole: absorption, excretion, and toxicity in six children.
J Infect Dis. 1973 Nov;128:Suppl:618-21 p. doi: 10.1093/infdis/128.supplement_3.s618.
3
Etiology of acute otitis media in infants and children.
Can Med Assoc J. 1966 Jan 22;94(4):159-63.

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