甲氧苄啶-磺胺甲恶唑与磺胺甲恶唑治疗儿童尿路感染的比较。
Comparison of trimethoprim-sulfamethoxazole with sulfamethoxazole in urinary tract infections of children.
作者信息
Feldman W, Johnson D M, Newberry P, Weldon A, Naidoo S
出版信息
Can Med Assoc J. 1975 Jun 14;112(13 Spec No):19-21.
Abstract
The effect of trimethorpim-sulfamethoxazole was compared with that of sulfamethoxazole alone in 26 children with urinary tract infection, randomly assigned according to a double-blind procedure to two equally sized groups. TMX-SMX was found to be superior in rendering the urine culture negative for the 3 months after the start of treatment. Also, over 12-month follow-up period there were fewer recurrences in the patients who received TMP-SMX but here the difference between the two groups did not reach statistical significance.
摘要
在26名患有尿路感染的儿童中，将甲氧苄啶-磺胺甲恶唑与单独使用磺胺甲恶唑的效果进行了比较。根据双盲程序，这些儿童被随机分为两个规模相等的组。结果发现，在治疗开始后的3个月内，甲氧苄啶-磺胺甲恶唑在使尿培养转为阴性方面更具优势。此外，在12个月的随访期内，接受甲氧苄啶-磺胺甲恶唑治疗的患者复发次数较少，但两组之间的差异未达到统计学意义。
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