非整倍体酵母减数分裂时染色体优先配对的证据。
Evidence of preferential pairing of chromosomes at meiosis in aneuploid yeast.
作者信息
James A P, Inhaber E R
出版信息
Genetics. 1975 Apr;79(4):561-71. doi: 10.1093/genetics/79.4.561.
Abstract
Meiotic pairing in homothallic S. cerevisiae was studied by tetrad analysis, using strains that were trisomic or tetrasomic for chromosomes. I. The disomic segregants of these strains produce tetrasomic spore colonies that can be distinguished by their phenotype. Results indicated the existence of preferential pairing and nonrandom assortment of chromosomes at meisosis I. The frequency of crossing over is apparently normal in at least some regions when nonpreferred pairing occurs.
摘要
通过四分体分析，利用对染色体三体或四体的菌株，研究了同宗配合型酿酒酵母中的减数分裂配对。I. 这些菌株的二体分离株产生可以通过其表型区分的四体孢子菌落。结果表明在减数分裂I时存在染色体的优先配对和非随机分配。当发生非优先配对时，至少在某些区域交叉频率显然正常。
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