Suppr超能文献

非洲绿猴基因组和染色质中高度重复DNA序列的排列

Arrangement of a highly repeated DNA sequence in the genome and chromatin of the African green monkey.

作者信息

Singer D S

出版信息

J Biol Chem. 1979 Jun 25;254(12):5506-14.

PMID:109436
Abstract

The DNA of the African green monkey contains three components that are distinguishable by the kinetics of reassociation. The rapidly reassociating component represents about 20% of the total DNA and is composed almost entirely of a sequence (AGMr(HindIII)-1) which is repeated 6.8 x 10(6) times. The majority of the AGMr(HindIII)-1 sequences are organized in long tandem repeats of a segment of 172 base pairs in length. However, a fraction of the AGMr (HindIII)-1 sequences is interspersed with another 37% of the genome. The structure of the chromatin containing the AGMr-(HindIII)-1 sequence is indistinguishable from that containing total DNA. Furthermore, there is nothing inherent in the nucleotide sequence of AGMr(HindIII)-1 which specifies a unique location for nucleosomes.

摘要

非洲绿猴的DNA包含三个可通过重缔合动力学区分的组分。快速重缔合的组分约占总DNA的20%,几乎完全由一个重复6.8×10⁶次的序列(AGMr(HindIII)-1)组成。大多数AGMr(HindIII)-1序列以长度为172个碱基对的片段的长串联重复形式排列。然而,一部分AGMr (HindIII)-1序列散布在基因组的另外37%中。含有AGMr-(HindIII)-1序列的染色质结构与含有总DNA的染色质结构没有区别。此外,AGMr(HindIII)-1的核苷酸序列中没有任何内在因素指定核小体的独特位置。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验