Singer D S
J Biol Chem. 1979 Jun 25;254(12):5506-14.
The DNA of the African green monkey contains three components that are distinguishable by the kinetics of reassociation. The rapidly reassociating component represents about 20% of the total DNA and is composed almost entirely of a sequence (AGMr(HindIII)-1) which is repeated 6.8 x 10(6) times. The majority of the AGMr(HindIII)-1 sequences are organized in long tandem repeats of a segment of 172 base pairs in length. However, a fraction of the AGMr (HindIII)-1 sequences is interspersed with another 37% of the genome. The structure of the chromatin containing the AGMr-(HindIII)-1 sequence is indistinguishable from that containing total DNA. Furthermore, there is nothing inherent in the nucleotide sequence of AGMr(HindIII)-1 which specifies a unique location for nucleosomes.
非洲绿猴的DNA包含三个可通过重缔合动力学区分的组分。快速重缔合的组分约占总DNA的20%,几乎完全由一个重复6.8×10⁶次的序列(AGMr(HindIII)-1)组成。大多数AGMr(HindIII)-1序列以长度为172个碱基对的片段的长串联重复形式排列。然而,一部分AGMr (HindIII)-1序列散布在基因组的另外37%中。含有AGMr-(HindIII)-1序列的染色质结构与含有总DNA的染色质结构没有区别。此外,AGMr(HindIII)-1的核苷酸序列中没有任何内在因素指定核小体的独特位置。