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Mechanisms of immune stimulation by bacterial DNA.

作者信息

Pisetsky D S

机构信息

Division of Rheumatology, Allergy and Clinical Immunology, Durham VA Medical Center, NC, USA.

出版信息

Springer Semin Immunopathol. 2000;22(1-2):21-33. doi: 10.1007/s002810000021.

DOI:10.1007/s002810000021
PMID:10944797
Abstract
摘要

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本文引用的文献

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Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide.CpG DNA和脂多糖对IL-12 p40启动子及p40分泌的差异调节
J Immunol. 1999 Jun 1;162(11):6770-5.
2
CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells.在没有抗原呈递细胞的情况下，CpG寡脱氧核苷酸可共刺激原代T细胞。
Eur J Immunol. 1999 Apr;29(4):1209-18. doi: 10.1002/(SICI)1521-4141(199904)29:04<1209::AID-IMMU1209>3.0.CO;2-J.
3
Immunostimulatory properties of genomic DNA from different bacterial species.
基于Toll样受体激动剂的传染病疫苗佐剂研发的最新进展
Pharmaceutics. 2022 Feb 16;14(2):423. doi: 10.3390/pharmaceutics14020423.
4
Sharpening up tumor microenvironment to enhance the efficacy of immune checkpoint blockade on head and neck cancer using a CpG-oligodeoxynucleotide.利用 CpG-寡脱氧核苷酸增强肿瘤微环境以提高头颈部癌症免疫检查点阻断的疗效。
Cancer Immunol Immunother. 2022 May;71(5):1115-1128. doi: 10.1007/s00262-021-03062-8. Epub 2021 Sep 28.
5
Toll-Like Receptor 21 of Chicken and Duck Recognize a Broad Array of Immunostimulatory CpG-oligodeoxynucleotide Sequences.鸡和鸭的Toll样受体21识别多种免疫刺激型CpG寡脱氧核苷酸序列。
Vaccines (Basel). 2020 Nov 2;8(4):639. doi: 10.3390/vaccines8040639.
6
Adjuvant Effect of Toll-Like Receptor 9 Activation on Cancer Immunotherapy Using Checkpoint Blockade.Toll 样受体 9 激活对免疫检查点阻断的癌症免疫治疗的辅助作用。
Front Immunol. 2020 May 29;11:1075. doi: 10.3389/fimmu.2020.01075. eCollection 2020.
7
Immunostimulatory Activities of CpG-Oligodeoxynucleotides in Teleosts: Toll-Like Receptors 9 and 21.CpG 寡脱氧核苷酸在硬骨鱼类中的免疫刺激活性：Toll 样受体 9 和 21。
Front Immunol. 2019 Feb 8;10:179. doi: 10.3389/fimmu.2019.00179. eCollection 2019.
8
CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses.为石斑鱼 toll 样受体（TLR）21 开发的 CpG-寡脱氧核苷酸可有效激活小鼠和人 TLR9 介导的免疫反应。
Sci Rep. 2017 Dec 11;7(1):17297. doi: 10.1038/s41598-017-17609-2.
9
Development of CpG-oligodeoxynucleotides for effective activation of rabbit TLR9 mediated immune responses.用于有效激活兔TLR9介导的免疫反应的CpG寡脱氧核苷酸的研发
PLoS One. 2014 Sep 30;9(9):e108808. doi: 10.1371/journal.pone.0108808. eCollection 2014.
10
Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish.Toll 样受体 9 和 21 具有不同的配体识别谱，并在斑马鱼中协同介导 CpG-寡脱氧核苷酸的活性。
Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20711-6. doi: 10.1073/pnas.1305273110. Epub 2013 Nov 26.
Immunobiology. 1999 Feb;200(1):106-19. doi: 10.1016/S0171-2985(99)80036-9.
4
The influence of base sequence on the immunological properties of defined oligonucleotides.碱基序列对特定寡核苷酸免疫特性的影响。
Immunopharmacology. 1998 Nov;40(3):199-208. doi: 10.1016/s0162-3109(98)00044-7.
5
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation.抗原呈递细胞的CpG-DNA特异性激活需要应激激酶活性，且在此之前会发生非特异性内吞作用和内体成熟。
EMBO J. 1998 Nov 2;17(21):6230-40. doi: 10.1093/emboj/17.21.6230.
6
Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.免疫刺激型CpG DNA快速诱导丝裂原活化蛋白激酶
J Immunol. 1998 Nov 1;161(9):4493-7.
7
Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs.腺病毒DNA中的序列基序可阻断刺激性CpG基序引发的免疫激活。
Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12631-6. doi: 10.1073/pnas.95.21.12631.
8
The influence of DNA sequence on the immunostimulatory properties of plasmid DNA vectors.
Hum Gene Ther. 1998 Jul 1;9(10):1439-47. doi: 10.1089/hum.1998.9.10-1439.
9
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.细菌DNA和免疫刺激型CpG寡核苷酸可触发小鼠树突状细胞的成熟和激活。
Eur J Immunol. 1998 Jun;28(6):2045-54. doi: 10.1002/(SICI)1521-4141(199806)28:06<2045::AID-IMMU2045>3.0.CO;2-8.
10
CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species.细菌DNA中的CpG基序通过pH依赖性活性氧生成激活白细胞。
J Immunol. 1998 May 15;160(10):4755-61.