Zatońska K, Bolanowski M
Katedry i Kliniki Endokrynologii i Diabetologii Akademii Medycznej im. Piastów Slaskich we Wrocławiu.
Pol Merkur Lekarski. 2000 May;8(47):356-9.
The review presents data from literature on the influence of endogenous and exogenous thyroid hormones on the activity of bone resorption and formation followed by enhanced bone loss and risk of osteoporosis. Thyroid hormones represent commonly prescribed medicines, often are used without control of their effects, especially in older patients at risk of fractures due to osteoporosis. The fracture risk increases in cases of untreated thyrotoxicosis, when administered suppressive doses of thyroxine, in postmenopausal women and patients with low peak bone mass. Fractures are more likely in parts of skeleton with cortical bone predominance e.g. distal forearm and hip.
这篇综述展示了来自文献的数据，内容是关于内源性和外源性甲状腺激素对骨吸收和形成活性的影响，随后会导致骨质流失加剧和骨质疏松风险增加。甲状腺激素是常用药物，常常在未控制其效果的情况下使用，尤其是在因骨质疏松而有骨折风险的老年患者中。在未经治疗的甲状腺毒症、给予抑制剂量甲状腺素的情况下、绝经后女性以及骨峰值低的患者中，骨折风险会增加。在以皮质骨为主的骨骼部位，如前臂远端和髋部，骨折的可能性更大。
