Sayama K, Lin S, Zheng G, Oguni I
Department of Animal Science, Faculty of Agriculture, Shizuoka University, Japan.
In Vivo. 2000 Jul-Aug;14(4):481-4.
To find whether green tea has anti-obesity effects in mice, female ICR mice were fed on diets containing 1, 2 and 4% green tea powder for 16 weeks and the body weight and food intake were weighed. After the administration of green tea, the ovaries, kidneys, adrenals, liver, spleen, brain, pituitary and intraperitoneal adipose tissues in the mice were weighed and lipid levels in the serum and in the liver and serum leptin levels were measured. It was found that body weight increase and intraperitoneal adipose tissues were remarkably suppressed by the administration of diets containing 2 and 4% green tea powder. Food intake was suppressed by feeding the 4% green tea diet. Concentrations of total cholesterol in the liver, triglycerides in serum and liver and nonestrified fatty acids in serum from mice which were administered green tea diet were lower than those in the controls. Leptin levels in serum showed a decrease with green tea treatments. These results indicated that lipid metabolism in mice was suppressed by the administration of green tea powder and thereby the fatty accumulation and body weight increase was suppressed.
为了探究绿茶是否对小鼠具有抗肥胖作用，将雌性ICR小鼠喂食含1%、2%和4%绿茶粉的饲料16周，并对其体重和食物摄入量进行称重。给予绿茶后，对小鼠的卵巢、肾脏、肾上腺、肝脏、脾脏、大脑、垂体和腹膜内脂肪组织进行称重，并测量血清和肝脏中的脂质水平以及血清瘦素水平。结果发现，给予含2%和4%绿茶粉的饲料可显著抑制体重增加和腹膜内脂肪组织。喂食4%绿茶饲料可抑制食物摄入量。给予绿茶饲料的小鼠肝脏中的总胆固醇浓度、血清和肝脏中的甘油三酯以及血清中的非酯化脂肪酸浓度均低于对照组。绿茶处理后血清瘦素水平降低。这些结果表明，给予绿茶粉可抑制小鼠的脂质代谢，从而抑制脂肪堆积和体重增加。
