Hasegawa Noboru, Yamda Norihiro, Mori Midori
Department of Food and Nutrition, Nagoya Bunri College, Nagoya, Japan.
Phytother Res. 2003 May;17(5):477-80. doi: 10.1002/ptr.1177.
The effect of powdered green tea on the lipid metabolism was studied in male Zucker rats fed a 50% sucrose diet containing 15% butter. The oral treatment of 130 mg powdered green tea per day depressed body weight increase and various adipose tissue weights but food intake was unaffected. The treatment also slightly increased the plasma triglycerides. These effects were likely mediated by the inhibition of lipogenesis in the adipose tissues. The experimental group had a higher concentration of liver total lipid, triglycerides and plasma protein, and lower liver weights than the controls. This may be due to lipid deposition in the liver because of the reduction in adipose tissue weights. It was found that powdered green tea lowered the plasma total cholesterol but liver total cholesterol was unaffected. The results indicate that the hypocholesterolemic activity of powdered green tea might be due to the inhibition of the synthesis of cholesterol in the liver.
在喂食含15%黄油的50%蔗糖饮食的雄性 Zucker 大鼠中研究了绿茶粉对脂质代谢的影响。每天口服130毫克绿茶粉可抑制体重增加和各种脂肪组织重量，但食物摄入量不受影响。该处理还略微增加了血浆甘油三酯。这些作用可能是通过抑制脂肪组织中的脂肪生成介导的。与对照组相比，实验组肝脏总脂质、甘油三酯和血浆蛋白浓度较高，肝脏重量较低。这可能是由于脂肪组织重量减少导致脂质在肝脏中沉积。研究发现，绿茶粉可降低血浆总胆固醇，但肝脏总胆固醇不受影响。结果表明，绿茶粉的降胆固醇活性可能是由于抑制了肝脏中胆固醇的合成。
