Li C, Dasgupta B
Department of Rheumatology, Southend Hospital, Westcliff-on-Sea, Essex, UK.
Clin Exp Rheumatol. 2000 Jul-Aug;18(4 Suppl 20):S56-7.
Low dose oral steroids (prednisolone 10-15 mg daily) are currently advocated for the treatment of uncomplicated PMR and the dose should be carefully adjusted in relation to disease activity. Intramuscular methylprednisolone has been shown to have a similar remission rate to oral steroids and a better side effect profile with respect to fracture rate and weight gain. Prophylaxis for osteoporosis at least with calcium and vitamin D should be initiated at the start of steroid therapy.
目前提倡使用低剂量口服类固醇（每日泼尼松龙10 - 15毫克）治疗无并发症的巨细胞动脉炎，且应根据疾病活动情况仔细调整剂量。已表明肌内注射甲泼尼龙与口服类固醇的缓解率相似，在骨折率和体重增加方面副作用更小。类固醇治疗开始时应至少使用钙和维生素D进行骨质疏松症预防。
