Nagai S, Hoshino Y, Hayashi M, Ito I
Dept of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Curr Opin Pulm Med. 2000 Sep;6(5):415-9. doi: 10.1097/00063198-200009000-00005.
Interstitial lung diseases (ILDs) encompass diverse clinicopathological disease entities ranging from idiopathic interstitial pneumonia (IIP) to interstitial pneumonia accompanied by collagen vascular diseases and diseases related to smoking, drug reactions, occupational environments, infections, and malignancies. Our focus is on the smoking-related interstitial lung diseases. Specifically, we focus on reports suggesting that chronic smoking is deeply involved in the disease pathogenesis and on reports suggesting that chronic smoking may influence the clinical course in terms of either disease severity or progression. Pulmonary Langerhans' cell granulomatosis (PLCG), desquamative interstitial pneumonia (DIP), respiratory bronchiolitis with interstitial lung diseases (RB-ILD), interstitial pneumonia associated with rheumatoid arthritis, acute respiratory distress syndrome (ARDS), and idiopathic pulmonary fibrosis (IPF) are covered.
间质性肺疾病（ILDs）涵盖了多种临床病理疾病实体，范围从特发性间质性肺炎（IIP）到伴有胶原血管疾病以及与吸烟、药物反应、职业环境、感染和恶性肿瘤相关的间质性肺炎。我们关注的是与吸烟相关的间质性肺疾病。具体而言，我们关注那些表明慢性吸烟与疾病发病机制密切相关的报告，以及那些表明慢性吸烟可能在疾病严重程度或进展方面影响临床病程的报告。涵盖的疾病包括肺朗格汉斯细胞组织细胞增多症（PLCG）、脱屑性间质性肺炎（DIP）、伴有间质性肺疾病的呼吸性细支气管炎（RB-ILD）、与类风湿性关节炎相关的间质性肺炎、急性呼吸窘迫综合征（ARDS）和特发性肺纤维化（IPF）。
