Hopkins W D, Rilling J K
Department of Psychology, Berry College, USA.
Behav Neurosci. 2000 Aug;114(4):739-48. doi: 10.1037//0735-7044.114.4.739.
The authors tested the theory that hemispheric specialization evolved as a consequence of reduced interhemispheric connectivity by examining whether neuroanatomical asymmetries were associated with variation in the ratio of corpus callosum size to brain volume (CC:VOL) and to neocortical surface area (CC:NEO) in human and nonhuman primates. Magnetic resonance images were collected in a sample of 45 primates including 8 New World monkeys, 10 Old World monkeys, 4 lesser apes, 17 great apes, and 6 humans. CC:VOL and CC:NEO were determined and correlated with measures of brain asymmetry. The results indicate that brain asymmetry significantly predicted CC:VOL and CC:NEO. Subsequent analyses revealed that species variation in functional asymmetries in the form of handedness are also inversely related to CC:NEO. Taken together, these results support the hypothesis that leftward brain asymmetries may have evolved as a consequence of reduced interhemispheric connectivity.
作者通过研究神经解剖学上的不对称是否与人类和非人类灵长类动物的胼胝体大小与脑容量之比（CC:VOL）以及与新皮质表面积之比（CC:NEO）的变化相关，来检验半球特化是半球间连接性降低的结果这一理论。对包括8只新大陆猴、10只旧大陆猴、4只小猿、17只大猿和6个人类在内的45只灵长类动物样本采集了磁共振图像。确定了CC:VOL和CC:NEO，并将其与脑不对称测量值相关联。结果表明，脑不对称显著预测了CC:VOL和CC:NEO。随后的分析表明，以利手形式存在的功能不对称的物种差异也与CC:NEO呈负相关。综合来看，这些结果支持了以下假设：向左的脑不对称可能是半球间连接性降低的结果。
