唾液腺作为基因转移在颅面应用中的模型。

Salivary glands as a model for craniofacial applications of gene transfer.

作者信息

Baum B J, Goldsmith C M, Hoque A T, Wellner R B, Baccaglini L, Ding C, Yamano S, Zheng C, Aframian D J, Zheng C, Aframian D J, O'Connell B C

机构信息

Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA.

出版信息

Int J Oral Maxillofac Surg. 2000 Jun;29(3):163-6.

PMID:10970076

Abstract

The potential applications of gene transfer technology to all branches of medicine are increasing. It is quite likely that within the next 10-20 years surgical practice routinely will utilize gene transfer, at least adjunctively. The purpose of this review is to familiarize the oral and maxillofacial surgeon with this technology. Studies performed with salivary glands in animal models are presented as examples of proof of concept.

摘要

基因转移技术在医学各个分支的潜在应用正在不断增加。很有可能在未来10到20年内，外科手术常规会使用基因转移技术，至少作为辅助手段。这篇综述的目的是让口腔颌面外科医生熟悉这项技术。以动物模型中的唾液腺进行的研究作为概念验证的例子呈现。