Barnett DA, Purves RW, Ells B, Guevremont R
Institute for National Measurement Standards, National Research Council of Canada, Ottawa, Ontario, Canada, K1A 0R6.
J Mass Spectrom. 2000 Aug;35(8):976-80. doi: 10.1002/1096-9888(200008)35:8<976::AID-JMS25>3.0.CO;2-Q.
Baseline separation of the three isomers of phthalic acid was achieved in a mixed gas system containing a 95 : 5 mixture of N(2) and CO(2), even though the acids could not be distinguished by high-field asymmetric waveform ion mobility spectrometry (FAIMS) when either pure N(2) or pure CO(2) was used as the carrier gas. Pseudomolecular anions of o-, m- and p-phthalic acids were generated by electrospray ionization and detected, following separation by FAIMS, using a quadrupole mass spectrometer. Addition of small amounts of CO(2) to an N(2) carrier gas also caused the compensation voltages to increase by as much as 12 V, accompanied by 2-7-fold improvements in the measured ion current and dramatic reductions in both adduct ion formation and parent ion fragmentation. Copyright 2000 John Wiley & Sons, Ltd.
在含有95:5的N₂和CO₂混合气体的系统中，实现了邻苯二甲酸三种异构体的基线分离，尽管当使用纯N₂或纯CO₂作为载气时，通过高场不对称波形离子迁移谱（FAIMS）无法区分这些酸。邻苯二甲酸、间苯二甲酸和对苯二甲酸的假分子阴离子通过电喷雾电离产生，并在通过FAIMS分离后，使用四极杆质谱仪进行检测。向N₂载气中添加少量CO₂也会使补偿电压增加多达12V，同时测量的离子电流提高2至7倍，加合离子形成和母离子碎片化都显著减少。版权所有2000 John Wiley & Sons, Ltd。
