Wlodkowski T J, Speck W T, Rosenkranz H S
J Pharm Sci. 1975 Jul;64(7):1235-7. doi: 10.1002/jps.2600640726.
Povidone-iodine is capable of specifically altering the DNA of living cells. This alteration may result in the induction of mutations of the base-substitution type. Because of the known relationship between mutagenic potential and the ability to induce cancer in animals, the present findings raise serious questions concerning the safety of this topical disinfectant.
聚维酮碘能够特异性地改变活细胞的DNA。这种改变可能导致碱基置换型突变的诱导。鉴于已知的诱变潜力与在动物中诱发癌症能力之间的关系，目前的研究结果引发了关于这种局部消毒剂安全性的严重问题。
