Thomlinson W, Berkvens P, Berruyer G, Bertrand B, Blattmann H, Brauer-Krisch E, Brochard T, Charvet A M, Corde S, Dimichiel M, Elleaume H, Estève F, Fiedler S, Laissue J A, Le Bas J E, Le Duc G, Lyubimova N, Nemoz C, Renier M, Slatkin D N, Spanne P, Suortti P
European Synchrotron Radiation Facility, Grenoble, France.
Cell Mol Biol (Noisy-le-grand). 2000 Sep;46(6):1053-63.
The application of synchrotron radiation in medical research has become a mature field of research at synchrotron facilities worldwide. In the relatively short time that synchrotrons have been available to the scientific community, their characteristic beams of UV and X-ray radiation have been applied to virtually all areas of medical science which use ionizing radiation. The ability to tune intense monochromatic beams over wide energy ranges differentiates these sources from standard clinical and research tools. At the European Synchrotron Radiation Facility (Grenoble, France), a major research facility is operational on an advanced wiggler radiation beamport, ID17. The beamport is designed to carry out a broad range of research ranging from cell radiation biology to in vivo human studies. Medical imaging programs at ID17 include transvenous coronary angiography, computed tomography, mammography and bronchography. In addition, a major research program on microbeam radiation therapy is progressing. This paper will present a very brief overview of the beamline and the imaging and therapy programs.
同步辐射在医学研究中的应用已成为全球同步加速器设施中一个成熟的研究领域。在同步加速器可供科学界使用的相对较短时间内,其紫外和X射线辐射的特征光束已应用于几乎所有使用电离辐射的医学领域。能够在宽能量范围内调节强单色光束使这些光源有别于标准的临床和研究工具。在欧洲同步辐射装置(法国格勒诺布尔),一个主要的研究设施在先进的摆动器辐射束端口ID17上运行。该束端口旨在开展从细胞辐射生物学到人体体内研究等广泛的研究。ID17的医学成像项目包括经静脉冠状动脉造影、计算机断层扫描、乳腺摄影和支气管造影。此外,一项关于微束放射治疗的主要研究项目正在推进。本文将简要概述该光束线以及成像和治疗项目。