Raake J L, Taeed R, Manning P, Pearl J, Schwartz S M, Nelson D P
Cardiac Intensive Care Unit, Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Respir Care. 2000 Sep;45(9):1105-12.
Blood gas analysis is extremely important in perioperative management of neonates with congenital heart disease, where ventilator manipulation of the pulmonary vascular resistance is crucial. Delays in blood gas analysis resulting from transport of samples to a central laboratory may compromise management of these patients. Furthermore, neonates with congenital heart defects may have lower arterial oxygen (PaO2) levels due to intracardiac right-to-left shunting. We evaluated the Sensicath System in neonatal patients following cardiac surgery by simultaneously measuring specimens on the central laboratory blood gas analyzer.
After patients returned from the operating room, the Sensicath System was connected to the arterial line. Blood was pulled across the sensor and re-infused to the patient after analysis. The accuracy and precision of the Sensicath System blood gas analysis results were assessed by comparison to simultaneous samples analyzed with a Corning 855 analyzer. The specimen-result turnaround time was recorded. 97 samples from 5 patients were compared.
Blood gas analysis results from the Sensicath System showed acceptable accuracy and precision: partial pressure of oxygen (PO2), r2 = 0.89, bias = -4.5 mm Hg, precision = 11.8; partial pressure of carbon dioxide (PCO2), r2 = 0.59, bias = -0.4 mm Hg, precision 6.2; pH, r2 = 0.78, bias = 0.03 mm Hg, precision 0.03. The central lab specimen-result turnaround time was 13.8 +/- 7.1 minutes. The Sensicath System provided results after a 60-second analysis time with no blood loss.
When compared to a Corning 855 blood gas analyzer, the Sensicath System was found to provide acceptable blood gas values, with no iatrogenic blood loss. This system may be especially helpful in infants with congenital heart defects, since rapid results are necessary for optimal patient care.
血气分析在先天性心脏病新生儿的围手术期管理中极为重要，其中对肺血管阻力的通气操作至关重要。将样本运送到中心实验室导致的血气分析延迟可能会影响这些患者的管理。此外，由于心内右向左分流，先天性心脏缺陷的新生儿可能具有较低的动脉血氧（PaO2）水平。我们通过在中心实验室血气分析仪上同时测量标本，评估了心脏手术后新生儿患者的 Sensicath 系统。
患者从手术室返回后，将 Sensicath 系统连接到动脉管路。血液通过传感器抽取，并在分析后重新输注给患者。通过与使用康宁 855 分析仪分析的同步样本进行比较，评估 Sensicath 系统血气分析结果的准确性和精密度。记录标本 - 结果周转时间。比较了 5 名患者的 97 个样本。
Sensicath 系统的血气分析结果显示出可接受的准确性和精密度：氧分压（PO2），r2 = 0.89，偏差 = -4.5 mmHg，精密度 = 11.8；二氧化碳分压（PCO2），r2 = 0.59，偏差 = -0.4 mmHg，精密度 6.2；pH，r2 = 0.78，偏差 = 0.03 mmHg，精密度 0.03。中心实验室标本 - 结果周转时间为 13.8 +/- 7.1 分钟。Sensicath 系统在 60 秒分析时间后提供结果，且无失血情况。
与康宁 855 血气分析仪相比，发现 Sensicath 系统可提供可接受的血气值，且无医源性失血。该系统对于先天性心脏缺陷的婴儿可能特别有用，因为快速获得结果对于优化患者护理至关重要。
