Tourniaire J, Pallo D, Fèvre M, Ponsin G, Mazenod B, Bachelot I, Sassolas G
Nouv Presse Med. 1975 Apr 26;4(17):1263-6.
An intravenous injection of synthetic LHRH (50mug) was given in 10 patients with prolactin secreting pituitary adenomas. Variations in circulating levels of gonadotrophic hormones were measured by radioimmunological estimation. The increase in blood level of luteinizing hormone was constant, low in three cases, normal in 3 and high in 4. An increase in follicle stimulating hormone (FSH) was absent in only two cases. The data obtained indicates the absence of any characteristic value of the LHRH test in the aetiological diagnosis of amenorrhoea/galactorrhoea syndromes. They represent an argument in favour of the relative character and of the functional nature of the gonadotrophic insufficiency of prolactin adenomas.
对10例分泌催乳素的垂体腺瘤患者进行了合成促黄体生成素释放激素(50微克)的静脉注射。通过放射免疫测定法测量促性腺激素循环水平的变化。促黄体生成素的血药浓度升高是持续的,3例升高程度低,3例正常,4例升高程度高。仅2例卵泡刺激素(FSH)未升高。所获得的数据表明,促黄体生成素释放激素试验在闭经/溢乳综合征的病因诊断中不存在任何特征性值。这些数据支持催乳素腺瘤促性腺功能不全的相对性和功能性本质。