Lefferts L Y
Food Addit Contam. 2000 Jul;17(7):511-7. doi: 10.1080/026520300412401.
In relation to residue variability and acute dietary intake, this paper considers whether or not consumers are adequately protected, and makes recommendations for governments and international bodies. Existing risk assessment science is inadequate to lay to rest some concerns raised by the scientific community, and it is plausible that acute exposures to pesticides from the most contaminated food may be causing adverse effects in some consumers. Consumers International recommends that: (1) analysis and regulation of pesticides with a common mechanism of action (e.g. organophosphate insecticides) be conducted in an integrated, aggregated manner, not on a single pesticide basis; (2) exposure to pesticides in foods consumed in large amounts by children be reduced by revising good agricultural practices; (3) clear risk assessment policies for acute risk assessments be established at the national and international level; and (4) an additional safety factor be applied in order to protect children when establishing maximum residue limits (MRLs) for pesticides in the absence of reliable data on the effects of pesticides on children (e.g. no pesticide-specific tests on immature animals for effects on the developing brain, endocrine, or immune systems).
关于残留变异性和急性膳食摄入量,本文探讨了消费者是否得到了充分保护,并为政府和国际机构提出了建议。现有的风险评估科学不足以消除科学界提出的一些担忧,而且从受污染最严重的食物中急性接触农药很可能正在对一些消费者造成不良影响。国际消费者协会建议:(1)对具有共同作用机制的农药(如有机磷杀虫剂)进行综合、汇总分析和监管,而不是基于单一农药进行;(2)通过修订良好农业规范,减少儿童大量食用的食品中的农药接触量;(3)在国家和国际层面制定明确的急性风险评估风险评估政策;(4)在没有关于农药对儿童影响的可靠数据时(例如,没有针对未成熟动物进行的关于农药对发育中的大脑、内分泌或免疫系统影响的特定测试),在制定农药最大残留限量(MRLs)时应用额外的安全系数以保护儿童。