Homewood C A, Moore G A, Wwarhurst D C, Atkinson E M
Ann Trop Med Parasitol. 1975 Sep;69(3):283-7. doi: 10.1080/00034983.1975.11687012.
Malarial pigment from erythrocytes infected with Plasmodium berghei was purified by treatment with sodium dodecyl sulphate solution, followed by incubation with Pancreatin. The purified pigment retained the apparently crystalline form of pigment within the parasite, rotated polarised light and had the same solubility characterisation as crude malarial pigment. It contained about 1% iron, all of which could be accounted for in terms of haemin. The iron of the pigment molecule is oxidised by the parasite to the ferric state.
用十二烷基硫酸钠溶液处理感染伯氏疟原虫的红细胞中的疟色素，然后用胰蛋白酶孵育，从而对其进行纯化。纯化后的色素保留了寄生虫体内色素明显的结晶形式，能使偏振光旋转，并且具有与粗制疟色素相同的溶解性特征。它含有约1%的铁，所有这些铁都可以用血红素解释。色素分子中的铁被寄生虫氧化为三价铁状态。
