Burchardt H, Busbee G A, Enneking W F
J Bone Joint Surg Am. 1975 Sep;57(6):814-9.
Fresh autologous segmental grafts of fibula, four centimeters long, were obtained from thirteen adult dogs. Holes were drilled in each before replantation. The amount of repair was determined after intervals of from four to twenty-four weeks. Torsional stress testing showed that the six drill holes 500 micrometers in diameter confined within an expanse of two centimeters did not mechanically weaken the transplants at the time of surgery. The drill holes were rapidly filled with cancellous bone which matured to cortical bone within twelve weeks. Microradiography and tetracycline labeling of drilled and non-drilled grafts demonstrated similar biological reparative patterns.
从13只成年犬身上获取了长度为4厘米的新鲜自体腓骨节段移植物。在重新植入前，在每个移植物上钻孔。在4至24周的间隔后，确定修复量。扭转应力测试表明，直径500微米、分布在两厘米范围内的六个钻孔在手术时并未对移植物造成机械性削弱。钻孔迅速被松质骨填充，松质骨在12周内成熟为皮质骨。对钻孔和未钻孔移植物进行的显微放射摄影和四环素标记显示出相似的生物修复模式。
