Barnetson R S, Halliday G M
Department of Dermatology (University of Sydney), Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Australas J Dermatol. 1997 Jun;38 Suppl 1:S63-5. doi: 10.1111/j.1440-0960.1997.tb01013.x.
Regression in epithelial skin tumours is a common phenomenon, and this may be partial or complete. In keratoacanthoma and familial self-healing epithelioma, nearly all the tumours regress completely. The incidence of total regression in melanoma and basal cell carcinoma is unknown, but in 25% of melanomas and 50% of basal cell carcinomas there is evidence of partial regression on histological examination. Previous studies carried out in our laboratories have indicated that regression of skin tumours is likely to be mediated by activated CD4+ T lymphocytes, possibly via cytokine secretion.
上皮性皮肤肿瘤的消退是一种常见现象，可能是部分消退或完全消退。在角化棘皮瘤和家族性自愈性上皮瘤中，几乎所有肿瘤都会完全消退。黑色素瘤和基底细胞癌完全消退的发生率尚不清楚，但在25%的黑色素瘤和50%的基底细胞癌中，组织学检查有部分消退的证据。我们实验室之前进行的研究表明，皮肤肿瘤的消退可能是由活化的CD4+ T淋巴细胞介导的，可能是通过细胞因子分泌。
