Clay H D
UCSF Medical Center, Department of Neurological Surgery 94143, USA.
J Neurosci Nurs. 2000 Aug;32(4):194-203. doi: 10.1097/01376517-200008000-00002.
The purpose of this study was to determine the validity and reliability of the SjO2 catheter in neurologically impaired patients. Cerebral hypoxia and ischemia are two of the most important causes of secondary injury after brain trauma. Early detection and treatment of cerebral ischemia may prevent additional damage to the injured brain. A critical review of literature was conducted by searching the Melvyl database system for the topic of monitor validity and reliability, dating back to 1927. A search of references from current articles also led to more classic studies. Attempts were made to find recent quantitative studies with an emphasis on the incidence of secondary brain ischemia detected by the tool. At best, the SjO2 catheter measures global cerebral oxygenation and is, therefore, unable to detect regional ischemia. In the literature reviewed, nearly 50% of the SjO2 oximetrix catheters provided an unreliable means for monitoring cerebral oxygenation. The initial milestones by Myerson et al. and Gibbs et al. have served as the basis for more refined research on cerebral tissue oxygenation and metabolism. The unreliability of the SjO2 catheter demonstrates how little we still know about cerebral physiology. In spite of the many advancements in healthcare technology, limiting secondary brain injury and improving neurologic outcome have remained elusive.
本研究的目的是确定SjO2导管在神经功能受损患者中的有效性和可靠性。脑缺氧和缺血是脑外伤后继发性损伤的两个最重要原因。早期检测和治疗脑缺血可预防对受伤大脑的进一步损害。通过在Melvyl数据库系统中搜索可追溯至1927年的监测有效性和可靠性主题,对文献进行了严格审查。对当前文章的参考文献进行搜索也引出了更多经典研究。试图找到近期的定量研究,重点是该工具检测到的继发性脑缺血的发生率。充其量,SjO2导管只能测量全脑氧合,因此无法检测局部缺血。在 reviewed的文献中,近50%的SjO2血氧饱和度导管为监测脑氧合提供了不可靠的手段。迈尔森等人和吉布斯等人的最初里程碑已成为对脑组织氧合和代谢进行更精细研究的基础。SjO2导管的不可靠性表明我们对脑生理学的了解仍然很少。尽管医疗技术有了许多进步,但限制继发性脑损伤和改善神经功能结局仍然难以实现。