Trifiletti R R, Restivo D A, Pavone P, Giuffrida S, Parano E
Department of Neurology and Neuroscience, Cornell University Medical College, New York, NY, USA.
Clin Neurol Neurosurg. 2000 Sep;102(3):163-5. doi: 10.1016/s0303-8467(00)00089-5.
Brucellosis is an infection due to Brucella species and is characterized by acute febrile illness, chilly sensations, sweats, weakness, generalized malaise, body aches and headache. The involvement of the nervous system is rare. A few cases have been reported with symptoms and sign of optic neuritis, meningoencephalitis, meningomyelitis and cranial nerve palsy. We report a case with culture proven neurobrucellosis who presented with diabetes insipidus along with systemic signs. Neuroimaging revealed multiple lesions in brain parenchyma, including the suprasellar region. Both diabetes and suprasellar lesions improved markedly with specific antibiotic therapy.
布鲁氏菌病是由布鲁氏菌属引起的一种感染，其特征为急性发热性疾病、寒战、盗汗、虚弱、全身不适、身体疼痛和头痛。神经系统受累较为罕见。已有少数病例报告出现视神经炎、脑膜脑炎、脊髓脊膜炎和脑神经麻痹的症状和体征。我们报告一例经培养证实的神经型布鲁氏菌病病例，该病例伴有尿崩症及全身症状。神经影像学检查显示脑实质内有多个病灶，包括鞍上区域。经特异性抗生素治疗后，糖尿病和鞍上病灶均明显改善。
