Korshak O L, Kotsiuba V L
Petro Bogach Research Institute of Physiology, Taras Shevchenko Kiev University.
Fiziol Zh (1994). 2000;46(4):8-16.
With using pharmacological analysis of stimulation or blockage of enterocytes cholin- or adrenergic receptors chronic experiments on dogs with gastric fistulas were carried out to study the influence of peptides on gastric acid secretion stimulated by pentagastrin or histamine. The different peptides (met- and leu-enkephalins, substance P, angiotensins I and II, oxytocin, pentagastrin) and internal secretion hormones (insulin, glucagon) were infused parenterally under the stimulated gastric secretion. It is proposed the model of the peripheral link of neurohumoral regulation of gastric acid secretion in the stomach.
通过对肠细胞胆碱能或肾上腺素能受体进行刺激或阻断的药理学分析，对患有胃瘘的狗进行了慢性实验，以研究肽对五肽胃泌素或组胺刺激的胃酸分泌的影响。在刺激胃酸分泌的情况下，将不同的肽（甲硫氨酸脑啡肽和亮氨酸脑啡肽、P物质、血管紧张素I和II、催产素、五肽胃泌素）和内分泌激素（胰岛素、胰高血糖素）经肠外注入。提出了胃内胃酸分泌神经体液调节外周环节的模型。
