孕鼠中尸胺的形成。

Formation of cadaverine in the pregnant rat.

作者信息

Andersson A C, Henningsson S, Rosengren E

出版信息

Acta Physiol Scand. 1979 Apr;105(4):508-12. doi: 10.1111/j.1748-1716.1979.tb00115.x.

DOI:10.1111/j.1748-1716.1979.tb00115.x

Abstract

The formation as well as the content of cadaverine were determined in different tissues of pregnant and non-pregnant rats. The placenta and ovary were most potent in the ability to form cadaverine. To our knowledge this is the first report of an in vitro formation of cadaverine linked to a normal physiological process, i.e. pregnancy. The highest concentration of cadaverine was found in the placenta and ovary of the pregnant rat. Treatment with aminoguanidine generally elevated the content of cadaverine, indicating a role of diamine oxidase as a regulator of diamine content.

摘要

测定了妊娠和未妊娠大鼠不同组织中尸胺的生成及含量。胎盘和卵巢生成尸胺的能力最强。据我们所知，这是首次报道与正常生理过程（即妊娠）相关的体外尸胺生成。在妊娠大鼠的胎盘和卵巢中发现尸胺浓度最高。用氨基胍处理通常会提高尸胺含量，表明二胺氧化酶作为二胺含量的调节剂发挥作用。