Finnegan L P, Kron R E, Connaughton J F, Emich J P
Int J Clin Pharmacol Biopharm. 1975 Jul;12(1-2):19-32.
To accomplish the assessment and treatment of abstinence in the infant of the drug dependent mother, a scoring system has been devised for use as a clinical and research tool. The score monitors the passively addicted infant in a more comprehensive and precise way than has previously been described, and permits us to be more objective in our clinical estimates of the abstinence syndrome. Further, this scoring system has been used by relating it to the dosage schedule of phenobarbital or paregoric as part of an ongoing research project designed to test the comparative usefulness of recommended treatments for neonates with abstinence symptoms. It has been found useful also in following the progression or diminution of symptomatology before, during and after drug therapy. Moreover, the scoring system provides a basis for developing uniform criteria for the assessment and treatment of the neonate of the addicted mother.
为了完成对药物依赖母亲所生婴儿戒断情况的评估和治疗,已设计出一种评分系统,用作临床和研究工具。该评分系统比以往描述的方法能更全面、精确地监测被动成瘾婴儿,并使我们在临床评估戒断综合征时更具客观性。此外,作为一项正在进行的研究项目的一部分,该评分系统已与苯巴比妥或樟脑酊的给药方案相关联,该项目旨在测试推荐治疗方法对有戒断症状新生儿的相对有效性。在药物治疗前、治疗期间和治疗后,该评分系统在跟踪症状的进展或减轻方面也很有用。此外,该评分系统为制定成瘾母亲所生新生儿评估和治疗的统一标准提供了依据。