Czlonkowska A
Neurol Neurochir Pol. 1975 Jul-Aug;9(4):441-6.
Twenty-three patients with Wilson's disease were studied. Using the rosette formation test it was found that the count of T-lymphocytes in the peripheral blood of these patients (29,77% +/- 12,58) was lower than in the control group (61,68% +/- 13,14). Using skin tests for demonstration of delayed hypersensitivity it was noted that in the group of patients the frequency of positive reaction with Candida albicans antigen was lower and these patients showed also less frequently positive reactions after DNCB immunization. The obtained results indicate that in Wilson's disease the functions of T-lymphocytes are distrubed. This may be the cause of previously observed hyperactivity of B-lymphocytes.
对23例威尔逊氏病患者进行了研究。通过玫瑰花结形成试验发现，这些患者外周血中的T淋巴细胞计数（29.77%±12.58）低于对照组（61.68%±13.14）。通过皮肤试验来证明迟发型超敏反应，结果发现患者组中白色念珠菌抗原阳性反应的频率较低，并且这些患者在二硝基氯苯免疫后出现阳性反应的频率也较低。所获得的结果表明，在威尔逊氏病中T淋巴细胞的功能受到了干扰。这可能是先前观察到的B淋巴细胞活性过高的原因。
