Arrivé L, Renard R, Carrat F, Belkacem A, Dahan H, Le Hir P, Monnier-Cholley L, Tubiana J M
Department of Radiology, and the Unit of Biostatistics and Medical Informatics, Faculté de Médecine, Hôpital Saint-Antoine, 184 Rue du Faubourg Saint-Antoine, 75571 Paris 12, France.
Radiology. 2000 Oct;217(1):69-74. doi: 10.1148/radiology.217.1.r00oc0669.
To develop and evaluate a scale for assessment of the methodological quality for clinical investigations of radiologic studies.
A scale was developed that included methodological standards compiled from established sources for assessing the methodological quality of study designs in clinical research and characteristics related to biases commonly observed in clinical radiologic research. The scale was composed of 15 standards and was tested with the results of 96 studies on imaging of liver hemangioma. Interrater reliability was measured between two observers by using percentage agreement and kappa statistics. Interrater reliability between two observers for a composite quality index that encompassed the 15 standards was measured with the intraclass correlation coefficient.
Agreement between the two observers was almost perfect (kappa value, 0.8-1.0) for 11 standards and substantial (kappa value, 0.74-0.78) for four standards. Agreement between the observers with regard to the composite quality index also was high (intraclass correlation coefficient r, 0.91 [95% CI: 0.87, 0.94]).
The scale appears to be reliable for the assessment of methodological quality of clinical investigations of radiologic studies.
制定并评估一种用于评估放射学研究临床调查方法学质量的量表。
制定了一个量表，其中包括从既定来源汇编的方法学标准，用于评估临床研究中研究设计的方法学质量以及与临床放射学研究中常见偏差相关的特征。该量表由15项标准组成，并通过96项肝血管瘤成像研究的结果进行了测试。通过使用百分比一致性和kappa统计量来测量两名观察者之间的评分者间信度。使用组内相关系数测量两名观察者之间对于涵盖15项标准的综合质量指数的评分者间信度。
对于11项标准，两名观察者之间的一致性几乎完美（kappa值，0.8 - 1.0），对于4项标准，一致性较高（kappa值，0.74 - 0.78）。观察者之间在综合质量指数方面的一致性也很高（组内相关系数r，0.91 [95% CI：0.87，0.94]）。
该量表似乎对于评估放射学研究临床调查的方法学质量是可靠的。
