Fogli L, Gorini P, Morsiani E
Divisione di Chirurgia Generale, Ospedale Bellaria, Azienda U.S.L. Città di Bologna.
Ann Ital Chir. 2000 May-Jun;71(3):285-91.
Fulminant hepatic failure (FHF) is a clinical syndrome characterized by the development of encephalopathy within eight weeks from the onset of the first symptoms, in the absence of previous hepatic disease. It is an uncommon but not rare disease, often fatal but potentially reversible. This article looks at the diverse aetiologies, clinical features, and current medical management, including orthotopic liver transplantation, and auxiliary orthotopic or eterotopic liver transplantation, that are the most recently adopted surgical procedures. Clinical experience with bio-artificial liver support systems of two of the most active research Groups in this field, concludes the paper.
暴发性肝衰竭（FHF）是一种临床综合征，其特征为在首次出现症状后的八周内发生肝性脑病，且既往无肝脏疾病。这是一种不常见但并非罕见的疾病，通常致命但有可能逆转。本文探讨了其多样的病因、临床特征以及当前的医学管理方法，包括原位肝移植、辅助原位或异位肝移植，这些是最近采用的外科手术。本文最后总结了该领域两个最活跃的研究小组在生物人工肝支持系统方面的临床经验。
