Lo Jamie O, Harrison Rebecca A, Hunter Alan J
School of Medicine, Oregon Health and Sciences University, 3515 SW US Veterans Hospital Road, Portland, OR 97239-2997, USA.
J Infect. 2007 Mar;54(3):e115-7. doi: 10.1016/j.jinf.2006.07.005. Epub 2006 Aug 30.
Syphilitic hepatitis is a rare but well described syndrome, typically manifesting as a mild clinical hepatitis, with complete resolution following therapy. There have been several cases of severe hepatitis, but none progressing to a fatal outcome. We present a case of fulminant hepatitis and hepatic failure in the setting of active secondary syphilis resulting in liver transplantation. The clinical syndrome of syphilitic hepatitis is discussed. This case should highlight and remind physicians of the varied and severe manifestations of syphilis, and prompt physicians to explore syphilis as a possible cause of unexplained hepatitis.
梅毒性肝炎是一种罕见但描述详尽的综合征，通常表现为轻度临床型肝炎，治疗后可完全缓解。已有数例严重肝炎病例，但无一进展至致命结局。我们报告一例在活动性二期梅毒背景下发生暴发性肝炎和肝衰竭并接受肝移植的病例。本文讨论了梅毒性肝炎的临床综合征。该病例应引起并提醒医生注意梅毒的多样且严重的表现，并促使医生探究梅毒作为不明原因肝炎可能病因的可能性。
