Gitschmann J, Nolte H
Acta Anaesthesiol Scand Suppl. 1975;60:55-9.
Etidocaine 1% and bupivacaine 0.5% (both with adrenaline 5 mug/ml) have been compared in a double blind study in epidural analgesia. Time of onset, duration, recession of analgesia and intensity as well as frequency of motor blockade were recorded in a selected group of patients undergoing varicose vein stripping. The onset of action of etidocaine was more rapid. Duration, recession and intensity of analgesia were similar for the two drugs. The main difference between them was that etidocaine produced a higher frequency and greater intensity of motor blockade.
在一项关于硬膜外镇痛的双盲研究中，对1%依替卡因和0.5%布比卡因（均含肾上腺素5微克/毫升）进行了比较。在一组接受静脉曲张剥脱术的患者中记录了起效时间、持续时间、镇痛消退情况、强度以及运动阻滞的频率。依替卡因的起效更快。两种药物的镇痛持续时间、消退情况和强度相似。它们之间的主要区别在于依替卡因产生运动阻滞的频率更高、强度更大。
