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芬兰本土一些含香豆素草本植物的抗菌活性

Antimicrobial activity of some coumarin containing herbal plants growing in Finland.

作者信息

Ojala T, Remes S, Haansuu P, Vuorela H, Hiltunen R, Haahtela K, Vuorela P

机构信息

Department of Pharmacy, Division of Pharmacognosy, Viikki Biocenter, P.O. Box 56, University of Helsinki, FIN-00014, Helsinki, Finland.

出版信息

J Ethnopharmacol. 2000 Nov;73(1-2):299-305. doi: 10.1016/s0378-8741(00)00279-8.

Abstract

Antimicrobial screening against selected Gram-positive and Gram-negative bacteria, yeasts, mold, as well as plant pathogenic fungi, with emphasis on method optimization was carried out on methanol extracts prepared from seven plants grown in Finland. Sensitivity to the extracts was found to vary considerably among the micro-organisms, the extract from Petroselinum crispum and Ruta graveolens showing the highest toxicity against Rhizoctonia solani. The growth of Heterobasidium annosum was inhibited, whereas that of Phytophtora (cactorum) was promoted by all the extracts. The antibacterial and antifungal activities of six natural coumarin compounds were weak, except for the inhibitory effect against Fusarium culmorum.

摘要

对从芬兰种植的七种植物中制备的甲醇提取物进行了针对选定革兰氏阳性和革兰氏阴性细菌、酵母、霉菌以及植物病原真菌的抗菌筛选,重点是方法优化。发现微生物对提取物的敏感性差异很大,皱叶欧芹和芸香的提取物对立枯丝核菌显示出最高毒性。所有提取物均抑制了异担子菌的生长,而促进了恶疫霉(樟疫霉)的生长。六种天然香豆素化合物的抗菌和抗真菌活性较弱,但对禾谷镰刀菌有抑制作用。

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