用包含完全弗氏佐剂的经足垫注射的灭活寄生虫未能保护小家鼠免受伯氏疟原虫感染。
Failure to protect Mus musculus against Plasmodium berghei with footpad injections of killed parasites incorporated in complete Freund's adjuvant.
作者信息
Reisen W K, Hillis T C
出版信息
J Parasitol. 1975 Oct;61(5):937-40.
PMID:1102649
Abstract
The stimulation of cell-mediated immunity by the injection of antigen from killed parasites incorporated in complete Freund's adjuvant did not protect Mus musculus from the erythrocytic stages of Plasmodium berghei. Agglutinating antibodies could not be detected, but delayed hypersensitivity was demonstrable. Apparently thymocyte sensitization alone was not sufficient to afford protection.
摘要
通过注射掺入完全弗氏佐剂的死寄生虫抗原刺激细胞介导的免疫，未能保护小家鼠免受伯氏疟原虫红细胞阶段的感染。未检测到凝集抗体，但可证明存在迟发型超敏反应。显然，仅胸腺细胞致敏不足以提供保护。
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