Siu T, Li W, Yudin AK
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
J Comb Chem. 2000 Sep;2(5):545-9. doi: 10.1021/cc000035v.
The spatially addressable electrolysis platform (SAEP) has been designed and constructed. It is demonstrated that the advantages of electrochemistry can be readily adapted to combinatorial chemistry and parallel synthesis formats. Parallel electrosynthesis of alpha-alkoxycarbamates, alpha-alkoxyamides, and alpha-alkoxysulfonamides via anodic oxidation of carbamates, amides, and sulfonamides, respectively, highlights the main features of the SAEP.
空间可寻址电解平台（SAEP）已被设计和构建。结果表明，电化学的优势能够很容易地应用于组合化学和平行合成形式。分别通过氨基甲酸盐、酰胺和磺酰胺的阳极氧化进行α-烷氧基氨基甲酸盐、α-烷氧基酰胺和α-烷氧基磺酰胺的平行电合成，突出了SAEP的主要特点。
