Uchida N, Tsuzuki Y, Ando T, Mochida Y, Yoshikawa M, Sekihara M, Kobayashi M, Ide M, Ohno Y, Kuwano H
Department of Surgery, Tone Chuo Hospital, Japan.
Breast Cancer. 2000 Jan;7(1):79-82. doi: 10.1007/BF02967193.
A proliferating trichilemmal tumor is relatively uncommon. It is composed of multiple cysts consisting of squamous epithelium with trichilemmal keratinization without granular layer interposition. This lesion usually occurs in the scalp of elderly women. We describe a 67-year-old woman with a malignant proliferating trichilemmal tumor in the skin over the breast. We first misdiagnosed the disease as a primary squamous cell carcinoma of the breast with a metastatic lymph node in the axilla because of the disease site and our unfamiliarity with the disease. The patient underwent radical mastectomy with axillary dissection. Eight months postoperatively, a tumor appeared in her right axilla and progressively enlarged. We subsequently excised the tumor. She is healthy as of 8 months postoperatively. To the best of our knowledge, only one case of a proliferating trichilemmal tumor occurring in the skin over the breast has been reported.
增殖性外毛根鞘瘤相对少见。它由多个囊肿组成，囊肿内衬鳞状上皮，有外毛根鞘角化，无颗粒层插入。该病变通常发生于老年女性头皮。我们报告一例67岁女性，其乳房上方皮肤出现恶性增殖性外毛根鞘瘤。由于病变部位及我们对该疾病不熟悉，最初我们将该病误诊为乳腺原发性鳞状细胞癌伴腋窝淋巴结转移。患者接受了根治性乳房切除术及腋窝淋巴结清扫术。术后8个月，她右侧腋窝出现肿瘤并逐渐增大。随后我们切除了肿瘤。术后8个月时她情况良好。据我们所知，仅有一例乳房上方皮肤发生增殖性外毛根鞘瘤的病例报道。
