Liu Xiaoliang, Li Wenzhong, Yuan Hepei, Gu Weihong, Chen Dawei
Department of Neurological and Cancer Surgery, The First Bethune Hospital, Jilin University, Changchun, Jilin 130021, P.R. China.
Department of Pathology, The First Bethune Hospital, Jilin University, Changchun, Jilin 130021, P.R. China.
Oncol Lett. 2016 Nov;12(5):3411-3416. doi: 10.3892/ol.2016.5113. Epub 2016 Sep 9.
The scalp is the most frequent site of occurrence of malignant tumors. As an area that is generally neglected by the patient and not closely monitored during physical examinations, scalp tumors can go unnoticed until they become malignant. The present study reports 3 cases of rare giant malignant tumors of the scalp, namely a peripheral nerve sheath tumor, a fibrous tumor and a malignant proliferating trichilemmal tumor, that were treated at The First Bethune Hospital of Jilin University (Changchun, China). Vascularized free anterolateral thigh flap surgery was performed in 2 of the 3 cases. A local flap repair was applied to the third case. The implanted skin grafts remained viable post-operatively and wound repair was uneventful. No signs of malignancy were detected on the edge of the pathological section upon closer pathological examination. In the follow-up period, no recurrence was detected in any of the cases.
头皮是恶性肿瘤最常见的发生部位。作为一个患者通常会忽视且在体格检查时未得到密切监测的区域,头皮肿瘤在恶变之前可能不会被发现。本研究报告了3例罕见的头皮巨大恶性肿瘤,即1例周围神经鞘瘤、1例纤维瘤和1例恶性增生性外毛根鞘瘤,这些病例均在吉林大学白求恩第一医院(中国长春)接受治疗。3例中的2例行带血管蒂游离股前外侧皮瓣手术。第3例采用局部皮瓣修复。术后植入的皮肤移植物存活良好,伤口修复顺利。经更仔细的病理检查,病理切片边缘未发现恶性迹象。在随访期间,所有病例均未发现复发。