Lee J G, Low A H, Leung J W
Division of Gastroenterology, UC Davis Medical Center, Sacramento, California 95817, USA.
J Clin Gastroenterol. 2000 Oct;31(3):233-6. doi: 10.1097/00004836-200010000-00010.
Indocyanine green has been reported previously as a useful agent for colonic tattooing, but its durability, ease of use, cost, and safety have not been compared with India ink. Eight pigs were randomized to colonic tattooing using sterile indocyanine green or India ink injected through tandem filters. The animals were recovered and killed after 2 weeks and were examined. All animals survived the study period with no complications. We identified 17 of 29 (59%) indocyanine green tattoos and 48 of 52 (92%) India ink tattoos at autopsy (p = 0.0003). Histologic reactions were mild and were distributed similarly in each group and the intensity of the tattoos diminished similarly in both groups. Although indocyanine green was slightly more expensive, it was easier to handle compared with India ink. Both indocyanine green and India ink tattoos cause only mild histologic reaction in the swine colon when examined 2 weeks after injection. India ink is superior to indocyanine green, when used for colonic tattooing.
吲哚菁绿此前已被报道为一种用于结肠纹身的有用试剂，但尚未将其耐久性、易用性、成本和安全性与印度墨水进行比较。八头猪被随机分为两组，分别使用通过串联过滤器注射的无菌吲哚菁绿或印度墨水进行结肠纹身。动物在2周后恢复并被处死，然后进行检查。所有动物在研究期间存活且无并发症。尸检时，我们在29个吲哚菁绿纹身中识别出17个（59%），在52个印度墨水纹身中识别出48个（92%）（p = 0.0003）。组织学反应轻微，两组分布相似，纹身强度在两组中均以相似方式减弱。虽然吲哚菁绿略贵，但与印度墨水相比更易于操作。注射2周后检查时，吲哚菁绿和印度墨水纹身均仅在猪结肠中引起轻微的组织学反应。用于结肠纹身时，印度墨水优于吲哚菁绿。
